Saturday, September 17, 2011

Insulin & Metabolic Rate ~ Am I Missing Anything?

As my regular readers are well aware, I've read a ton of peer review research on insulin and its action.  I also have a pretty freakish memory for certain things, so if I'd come across even an aside from a reputable source, I would have remembered it.  

So, I have yet to come across any information that insulin directly alters metabolism.  By that I mean the basal metabolic rate to keep you live and not-so-kickin -- BMR/RMR/REE.  As close as it comes is that insulin stimulates glycolysis (oxidation of glucose for energy), but it also suppresses fatty acid metabolism so that would seem to be a wash to me -- substrate switch but no impact on total rate of fuel burning.  I'm also not talking about minor differences in the TEF for carbs vs. other macros as this does not appear to be related to hormones per se.  

I'm talking whether insulin has any known action like that of leptin that specifically increases or decreases metabolic rate.  Have I missed anything?

Thanks in advance!

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