Diazoxide, Insulin & Obesity

In his recent post on insulin and obesity, Fat Tissue Insulin Sensitivity and Obesity , Stephan brings up one of those *nagging* studies that have been touted by TWICHOO advocates for quite some time.

Back in May 2008, Peter/Hyperlipid posted Weight loss when it's hard 2. Diazoxide.  This discusses the following study:  Beneficial Effect of Diazoxide in Obese Hyperinsulinemic Adults.

What is diazoxide?  It is a drug that reduces insulin secretion.  As Peter writes:

You can simply reduce insulin secretion using diazoxide. Find enough obese people willing to put up with the hunger generating regime supplied by Slimfast and semi starve them for 8 weeks. Half can have a placebo, half get diazoxide in addition to Slimfast starvation. Figure 1 in the results is where you want to look. The idle porkers starving on Slimfast plus diazoxide lost significantly more weight in 8 weeks than the idle porkers starving on Slimfast alone.

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