In an interview with Andreas Eenfeldt (some time in 2010, uploaded by Eenfeldt 3/15/11), Gary Taubes makes the following statement (~3 minute mark is a good place to start):
Look it's 2010 we have a disorder of excess fat accumulation, and people are saying that the actual physiological regulation of fat tissue is irrelevant.
One point Stephan made in his retracted response to Gary's recent blog post needs to be addressed. So I'll do so here. Folks have been letting Taubes get away with this for a very long time, and that is his indiscriminate use of the word "regulation". The core principal of TWICHOO (Taubes Wrong Insulin-Carbohydrate Hypotheses of Obesity) is that insulin is the primary regulator of fat tissue metabolism, and thus fat mass. He's actually ratcheted that up a notch so that in his view insulin acts as virtually the sole regulator.
I'm going to use a computerized multi-fuel furnace with a fuel tank system depicted below to make my analogies.
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