24hr Profiles: Insulin Secretion & Clearance in Normal and Obese

In this post I want to discuss two companion studies from the late 80's looking at twenty-four hour profiles of insulin secretion, uptake by the liver, glucose levels, etc.  The studies are available at the links below:

(I)  Quantitative Study of Insulin Secretion and Clearance in Normal and Obese Subjects

(II) Twenty-Four-Hour Profiles and Pulsatile Patterns of Insulin Secretion in Normal and Obese Subjects


Participants:  All non-diabetic with no family history of diabetes.  Age, weight, BMI are group averages.

14 normal weight:  7M/7F,  age 38.5 yrs, weight 70.1 kg, BMI 23.0
15 obese:  5M/10F, age 35.8, weight 105.7 kg, BMI 37.0

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