The confusion with this whole mitochondria-based theory of obesity continues. I'm not sure what's driving this other than a desperate clinging to the notion that one's obesity can not be the result of one's overeating and/or sedentary lifestyle, however they came about. The more I read on this the more bizarre it all seems, but it comes down, once again, this notion that "fat burning" is related to fat accumulation or loss. This is nonsense. If your body requires 2000 cal/day to meet energy needs, it's pretty much all the same to your body where it gets that energy from. And it will always be getting its energy from some mix of substrates: glucose, fatty acids, and yes, amino acids and ketones. Nobody disputes that energy is partitioned and substrates are oxidized in different manners largely at the direction of hormones ... insulin and leptin having well characterized roles in this regard.
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