Sunday, October 16, 2011

24 Hour Leptin Profiles ... Sleep Off Your Spiked Leptinade?

In Science Krispies ... Spiked Pink Leptinade Anyone?,  I took on Dr. Ron Rosedale's claim  that "glucose spikes leptin".  The study I highlighted looked at 9-hour insulin and leptin profiles holding protein constant and essentially comparing a near-zero carb meal to a near-zero fat meal and fasting.  I've copied that graphic to this post:
A&B = women, C&D = men

OK, so we do see that the HC meal results in slightly elevated leptin, more pronounced in women, delayed about 4-5 hours after the meal vs. HF or fasting.  Over on the Perfect Health Diet blog (thanks for the shout out Paul!) , Paul Jaminet wrote:  
CarbSane partially confirms Dr. Ron Rosedale: eating carbs does raise leptin levels compared to eating fat, but it is a mild rise over an extended period of time, not a “spike.”
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