Wednesday, November 16, 2011

The Brain Rules ~ But Which Part?

The fact that the brain, or centralized neural complexes, even exists in multicellular higher organisms is indicative of it's over-arching governing function.  Sure, we have feedback loops in our bodies that seem to have little if any mediation by centrally produced signals, but ultimately our organs, including our fat tissue, ultimately relay information to our brains.  Our brains then send out signals back to the organ, and to other organs.  Renowned endocrinologist Julius Bauer -- heralded originally by Gary Taubes in GCBC, and now in a recent blog post -- said as much.  

I've been reading a lot of truly nasty commentary about the web ever since Stephan began rolling out the food reward series.  Apparently a lot of people have hurt feelings and think that Stephan is now yet just another young skinny male just looking to blame fat chicks for their obesity, by -- gasp! -- discussing how leptin alters appetite and food intake in the brain.  Ya know, I do share the sentiment regarding the seeming dominance of the field of all nature of obesity experts tending to be lean males, trying to figure it all out in a population dominated more by females.  But that impacts my views on advice given and such ... I cannot let it cloud my judgment as regards what the science actually says.  This is the crux of this matter of obesity research and such.  Anyone can fashion a hypothesis that makes sense to them.  But if it is not consistent with the actual results observed in carefully controlled experiments, it's just wrong!  Conversely, I don't care if Stephan were actually Homer Simpson if the science he's conveying to his audience is sound.   And yet, sadly, I think most obese are beyond "repair" in terms of ever experiencing that nirvana of subconscious homeostasis of a lean body weight.  That doesn't mean it's not attainable, just that it will take some conscious effort.  Before I discuss that a bit, I just can't help but highlight a comment Taubes made recently on his blog:  
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