Sunday, December 5, 2010

Fat Accumulation: Taubes v. Frayn ~ ASP in vivo in humans

This is actually a re-posting of the cited article, but I've updated the post significantly since the original.

Coordinated release of acylation stimulating protein (ASP) and triacylglycerol clearance by human adipose tissue in vivo in the postprandial period  Jumana Saleh,* Lucinda K. M. Summers,† Katherine Cianflone,1,* Barbara A. Fielding,†Allan D. Sniderman,* and Keith N. Frayn.  1998.

This paper demonstrated ASP actions in vivo for humans in the postprandial (post-meal) period.  ASP levels were measured locally to the adipocytes  (venous output side) and systemically in the arterial "supply" side.  This was important because many who would dismiss the action of ASP look at systemic ASP levels and claim no connection.  However, this paper demonstrated otherwise:

Abstract 

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