Metabolic Fate of Chylomicron Phospholipids and Apoproteins in the Rat
The researchers injected radiolabeled chylomicrons into rats to determine the fate of the components. The results:
Catabolism of chylomicrons is associated with a rapid transfer of phospholipid, apoA-I, and possibly apoA-IV into HDL. Chylomicron phospholipid appears to give rise to vesicles which are probably incorporated into preexisting HDL. Chylomicron surface components may be an important source of plasma HDL.
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