In the previous post in this series, we met the C3KO mouse, a mouse that is ASP deficient. In this post, I'm going to discuss what happens when you take a leptin-deficient ob/ob mouse and also make it a C3KO. Humor me my fun with Star Wars characters ;-)
It turns out I had discovered this study and blogged on it over a year ago: Acylation-stimulating Protein (ASP) Deficiency Induces Obesity Resistance and Increased Energy Expenditure in ob/ob Mice (Xia, Sniderman & Cianflone).
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