Showing posts with label Carbohydrates. Show all posts
Showing posts with label Carbohydrates. Show all posts

Thursday, August 15, 2013

Bump: The Diabetes "Crash" Cure & Pancreatic Fat

Today's 8/15/13 bump was inspired by a comment by Tsimblist (thanks!) alerting me to this paper:  Type 2 Diabetes Etiology and reversibility
Reversal of type 2 diabetes to normal metabolic control by either bariatric surgery or hypocaloric diet allows for the time sequence of underlying pathophysiologic mechanisms to be observed. In reverse order, the same mechanisms are likely to determine the events leading to the onset of hyperglycemia and permit insight into the etiology of type 2 diabetes. Within 7 days of instituting a substantial negative calorie balance by either dietary intervention or bariatric surgery, fasting plasma glucose levels can normalize. This rapid change relates to a substantial fall in liver fat content and return of normal hepatic insulin sensitivity. Over 8 weeks, first phase and maximal rates of insulin secretion steadily return to normal, and this change is in step with steadily decreasing pancreatic fat content.
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Monday, May 13, 2013

Stick a Toothpick in It? Taubes' 4-pronged Carb/Insulin "Fork" Loses its Tines

I'm bumping this today, because in the weeks to come I hope to update, flesh out, and reference it fully.  Looking back at something written almost 2 and a half years ago it seems rough, but nonetheless it  still summarizes what I call TWICHOO and the arguments against it pretty well.  



This post updated slightly 6/22/2012.   Original publication date 1/23/11

In the comments at Jimmy's blog on my interview podcast, several comments either directly or by inference say I failed to make my case against Taubes.  Well, I think I did pretty much get to what I consider the four prongs of Taubes carb/insulin hypothesis, but I've decided to try and summarize this in a blog post.  Another common comment is that I'm somehow nit-picking at minutia, basically if folks lose weight on low carb, it doesn't matter the details of why.  To those, if they are reading this, I would say that any objective view of my arguments would lead to the conclusion that these are NOT minor details, they are the sum total of Taubes' evidence in support of his hypothesis.  Not only has he NEVER debunked the calorie-based theories on obesity, but almost all evidence in support of his "alternate" theory HAS been.  

I will not be referencing this post, it's all been done before here, and I don't have the time to trace down every link etc.  


So, what do the four prongs of the fork stuck in the potato above represent?  
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Thursday, April 4, 2013

A Matter of Control

Bump.


Original Publication 12/10/2011

It seems to me that many people misinterpret -- at least in their minds -- the meaning of this word when it is used in the scientific context.   While most of those no doubt understand the concept, after hearing the term enough, it just seems it comes to mean something else to them after a while.  I submit as evidence, statements made by two popular bloggers.  

First up, J. Stanton at gnolls.org with How “Heart-Healthy Whole Grains” Make Us Fat.   Wait!!  Did you click that link already?  I forgot to caution you that the post you are about to read contains science, so you might want to proceed with caution.  < / sarcasm > .  Anyway, the study he discusses in that post is:  High Glycemic Index Foods, Overeating, and Obesity.  Stanton prefaces his discussion with the following:
Yes, I admit to a degree of hyperbole—but this study is so well instrumented and controlled, and its results so informative, that I believe it’s important for everyone to read it.
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Monday, January 14, 2013

The Problem with Science in the Incestral Health Community

I've been discussing lately the entangled web of relationships and referencing in this community, and I have decided that henceforth I'm going to call it on this blog what I've called it in my head for a very long time:  The Incestral Health Community.   This is because everyone has ties to everyone else (or enough) and apparently nobody feels even the slightest bit interested in vetting one another, let alone any professional obligation to do so before slapping the affiliate logo on their website or inviting fellow IHC members to speak at their events.  

I've also been highlighting credentials of late, and will continue to do so when I feel that it is pertinent.  I want to make sure that everyone reading here understands that I am not passing judgment on anyone's academic record, highest degree held, etc.  Fer crying out loud, two of the smartest women I've had the privilege of knowing both dropped out of high school in the 9th grade.  And sadly, the number of functional illiterates matriculating at prestigious institutions these days is mind-blowingly astounding. This is not about academic elitism or snobbery.  It IS about discussing just what makes for an authority, an expert, etc.
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Thursday, December 20, 2012

Robb Wolf: On the Role of Calories vs. Carbs/Insulin

... but it was my new-found energy and activity level that drove my leanness, not an inability to store fat in the absence of significant insulin. I think this is one of the most damaging messages that comes out of the LC camp to this day, I was duped by this, so I’m not going to do what a lot of other recovered LC writers do and make folks out to be idiots for still believing this…but, it is time to face facts. In every damn study it is clear that for fat loss we’d like adequate protein, and a calorie restriction scenario.
Robb Wolf, Dec. 2012

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Saturday, November 24, 2012

Is SuperStarch a Safe Starch?

Remember "safe starches"?   This whole SuperStarch thing reminded me of that for some reason.  It was just a little over a year ago that Jimmy Moore sent out the email to all of the experts he considers experts to inquire over the safety of consuming starches.  It mattered not the quality of the response, he published them all up.  This post put the pry bar in whatever cracks there were in the community along carbohydrate lines and was the source of much of the antagonism Jimmy decries.  Some responses of interest:
Jeff Volek: Claiming you need carbs to prevent scurvy is a red flag this guy is a nut job. Tell him to eat a red pepper. There is no evidence what so ever the human body has any dietary requirement for the nutrient class of carbohydrate (i.e., there is no defined condition associated with not consuming carbs).
This comment just demonstrated that UCAN be an asshat in LLVLC-land so long as it's not against a low carber.   Next up, the other Bobsie Twin of the pair.  He's not on the UCAN board, but it's kind of hard to separate yourself from the energy drink biz of someone you are so tightly associated with in the LC community.  
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Monday, November 19, 2012

SuperStar(ch) -- Or does something stink here?

image link
How on earth did SuperStarch fly under my radar?   Thanks to Lerner, I was made aware of the connection between Jeff Volek -- of nutty ketosis and Atkins Nutritionals fame -- and the UCAN Company marketing a new type of sports drink containing SuperStarch (TM and all that near as I can tell, though the term is not unique to the company).    When I think of SuperStarch, the image of Molly Shannon's Mary Katherine Gallagher character from SNL just popped into my mind complete with her "superstar" exclamation.  Suparstarch(aching?)  Methinks so!

The bottom line of what I'll abbreviate as SS, is that it is supposedly better for performance -- presumably specifically in endurance activities -- because it effectively provides a slow release glucose source that is low GI (doesn't spike glucose much), doesn't elicit a significant insulin response, and therefore doesn't suppress fat burning.  Some of which may be true, and some of which is not supported by the evidence provided by the company.  


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Tuesday, May 22, 2012

Quality Low Carb Science?

A while back I asked if anyone had any evidence that insulin blocks leptin action in the brain.  There were many responses both here and on Twitter -- thanks!! -- one of which referenced the following study:  Suppression of insulin secretion is associated with weight loss and altered macronutrient intake and preference in a subset of obese adults, PA Velasquez-Mieyer, PA Cowan, KL Arheart, CK Buffington, KA Spencer, BE Connelly, GW Cowan, and RH Lustig.  If you're the person pointed me to this, I apologize for not naming you.  Ahhhh Robert Lustig.  Haven't spent much time on him here, but as he muscles his way into the (misguided) War on Insulin, this too shall change.  

I will have much more to say about that study on the whole at some future date.  They gave some people an insulin-lowering drug (a drug that does more than just suppress secretion) and some lost "significant" weight, some lost a wee bit, and some even gained weight.  In reading the intro, I'm becoming increasingly dejected over the quality of peer review these days ... but that too will be part of the subsequent analysis of this study as a whole.
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Sunday, March 11, 2012

Why We Get Fat ... Lessons from a Cafeteria Rat

{Original publish date:  2/25/11}


(Hat tip to Beth for bringing this to my attention)

This study used male Wistar rats

{eek ... I'm having flashbacks to a former career!}

This rat is not a genetic mutant predisposed towards obesity, but is often used in diet induced obesity (DIO) studies, as they will fatten considerably on a high fat diet.
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Sunday, February 26, 2012

Live Blogging from the Paleo Summit I: Mark Sisson

Link:  Mark Sisson

Ratings:

☼ ☼ ☼ ☼ ☼  Entertainment Value
☼ ☼ ☼ ☼ ☼  Content
☼ ☼ ☼ ☼ ☼  Informational Accuracy
☼ ☼ ☼ ☼ ☼  Overall

Summary:
It is fair to say that of all the paleo/LC folks with whom I have disagreements with on the substance of their message, Mark Sisson is probably the most enjoyable personality to listen to.  If you know nothing about paleo/primal, this is a good overview of the basics.  If you're familiar with Primal Blueprint at all, there's nothing new here.  The interview is more notable for what it is missing -- any major emphasis on excessive carbohydrate consumption (no carbohydrate curve), minimal mentions of insulin and no mention of fat being locked away.  Not too many overt factual errors or misrepresentations of the science.  Most of all this interview and other recent ones demonstrate Mark's ability to adjust his marketing pitch to the tune of what's going on out there.   His transition has been so smooth as to be almost unnoticeable.  The hot thing these days is the "fat burning metabolism", and Mark's a master at capitalizing on that.

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Tuesday, February 14, 2012

Separating Carbs & Fats ~ My Rationale

I get a fair amount of traffic here from time to time thanks to my posts about Zoe Harcombe and the Harcombe Diet.  Zoe's dietary philosophy boils down to parroted Taubesian Pseudophysiology, but one of the things she advocates, that I've discussed here before, is the strategy of separating carbs and fats and having them at different meals.  She makes a lot of comments about how calories don't count and all that too ... so the Google searches on her name and/or CICO or the separating carbs & fats thing tend to land folks here at the Asylum.  As a result, apparently just enough folks know enough about my stance on carbs & fats to misrepresent my position in discussions about the web.  More than once I've been described as subscribing to "that old food combining nonsense" or things along that line.  I've long since passed the point where I could answer to these various misconceptions everywhere they are found, but in this case, it's happened enough times that I thought I'd set the record straight on this issue.
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Saturday, December 17, 2011

Fasting Insulin & Diet ~ Time for some Cognitive Dissonance?

Reader Josh brings this study to our attention:


Huh?  They compared dietary intake (24 hour recall) for 1069 non-diabetics (assessed by administering a glucose tolerance test) with fasting insulin levels.  
Subjects were seen for up to three visits from 1984 to 1992. A 24-h diet recall and fasting insulin concentrations were collected at all visits....
... High total and saturated fat intake were associated with higher fasting insulin concentrations after adjusting for age, sex, ethnicity, body mass index, waist circumference, total energy intake and physical activity. Dietary fibre and starch intake were inversely associated with fasting insulin concentrations....
... Associations were similar in men and women and for active and inactive subjects, though associations of fibre and starch intake with insulin concentrations were strongest in lean subjects. 

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Thursday, December 15, 2011

Safe v. Non-Toxic

I've been listening and reading about the web, and the "buzz" over so-called "safe starches" continues.  One of the sentiments that goes with this is the idea that somehow Paul Jaminet is being irresponsible by promoting starch consumption.  The rationale is that because some minority of the population is intolerant to certain starchy foods, at best we should be labeling foods like potatoes and white rice "non-toxic" starches.  I disagree.  Firstly, in their book and on the blog, the Jaminets' reason for designating certain starches as safe couldn't be much more clear.   Secondly, I don't like the word toxic associated with a substance found in natural foods that has sustained billions of human lives throughout many millenia.  

There are a certain number of people who are wildly allergic to peanuts.  Should every book or nutritionist that allows peanuts, or even encourages peanut butter as a good choice for snacks tag them semi-toxic?  In my opinion, the fact that there are some folks with celiac does not justify the demonization of wheat consumption for all people.  Then we have nightshades.  Should we start talking about "non-toxic" fruits and veggies because some seem sensitive to these foods?  

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Friday, October 28, 2011

Keep the Leptinade flowing! I'm going to die from my glucose anyway ...

A few general thoughts on this whole "safe starches" tangent into Ron  "Everyone's a Diabetic" Rosedale's contentions.  I was prompted to look into many of the claims of Rosedale by a short conversation I had with him over at PaleoHacks that can be found scrolling down to his responses here.  When one goes and reads the Facebook links in the root post, it is clear that Rosedale's views are pretty extreme as regards blood glucose levels, diabetes, etc.  It comes down, really, to viewing all blood glucose, leading to any level of glycation, as harmful.  Basically through Rosedale-colored glasses we see circulating glucose as always harmful and to be kept minimal both in circulation and as cellular fuel as much as possible for optimal health.  He also advocates getting virtually no glucose from your diet, relying, instead on your liver for all glucose needs.   Glycation debilitates, deteriorates and ultimately kills you, and in Rosedale's opinion, there's no "safe" level of glucose and its insidious glycation that causes no harm.  

As such, Jimmy Moore published a rebuttal to the rebuttal of sorts by Rosedale in response to Paul Jaminet of Perfect Health Diet.  Now, I think it's probably known to most of my readers that Paul is perfectly capable of responding eloquently to this, and I most certainly do not want to be seen as stepping on any toes.  But I think Jimmy's massive data dump blog posts -- liberally speckled with various uncalled for responses from LC luminaries -- deserve as many dismantlings as bloggers out there are willing to put up.  Law of numbers and all that, and hopefully some of this nonsense can be dispelled before we layer even more myths on a list that is already too long in low carb circles.

And so, with my previous post, I decided to focus on this notion that there is no such thing as a safe starch because there's no such thing as a safe glucose level, and look at some of the references Rosedale provided to make the case that this is "clearly" so.
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Monday, October 10, 2011

Warning: This food contains starch. Consult your doctor before consuming!

In the comments section of Jimmy's "safe starch" post, Jimmy had this to say:
I'm still concerned with the use of the phrase "safe starches" because people will think that is universally true--and it may not be. Perhaps calling them "potentially safe starches" with the caveat that you should be checked by a physician to determine if they are safe for you or not would be better.
Has low carb dogma really come to this?  Where a couple of scientists with some health issues work them out with what appears to me to be exhaustive research, share their results with others in the form of a book, and are basically being accused of possibly harming people by suggesting that some starches are safe?
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Thursday, September 1, 2011

Gary Taubes speaks ...

http://www.latestinpaleo.com/blog/2011/8/29/latest-in-paleo-30-gary-taubes.html

If you're in the mood for a little torture ;-)

He knows more than all those bloggers out there about those Pima!  (~21:30)  If this is the case, why does he still use them as examples?

He discusses AHS/Stephan Guyenet (~34:30).  Of note, this was obviously recorded recently.  He could have taken the opportunity to apologize publicly to Stephan.  Since he didn't address that specifically, the ticker stays.
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Tuesday, August 16, 2011

Guyenet v. Taubes: Thoughts on Stephan's Demolition of the Carbohydrate Hypothesis of Obesity

I've been laying kinda low on Stephan Guyenet's disassembling of Taubes' "Carbohydrate Hypothesis" and just sort of soaking in some of the responses.  However as the mood hits, I'll be sharing some thoughts on the reaction in the coming days.  

This post, however, relates to his blog post.  As I said in the comments on his blog:  Well done!  Most of the arguments he makes are not new to this blogger, but I think these things need to be stated by as many bloggers as many times as is needed -- and judging from the reactions the work in this regard may never be done!! -- until the following acronym becomes as common in LC circles as acronyms like ACE, OWL and CCL are to Atkins dieters. When Taubes' theories become known as Taubes' Wrong Insulin-Carbohydrate Hypothesis On Obesity - TWICHOO.  It kinda rolls off the tongue!
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Wednesday, August 10, 2011

Red Meat Induced Blog Traffic Spike ...

I'm flabbergasted that (before even Stephan posted his comment here)  Blogger registered a "spike" in my traffic (and we're talking the "instantaneous" 2 hour hits kind) worthy of the blood glucose curve for Wheat Belly consuming 5 bowls of battery acid.  Stephan's comment has obviously been linked to at www's far and wide and generated more, but this is something *different* here, even given my penchant for those Gary Taubes exposes seen as provocative.

In the three days since the Wonder what he said post was published, it has rocketed up my most viewed posts to be #2 ALL TIME and as of this post, half the page hits of the long standing #1 GT email post.  

What does this say folks?  
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