Ketogenic Triathlete?

I noticed a little traffic blip to my posts here on SuperStarch scamming which reminded me that AHS13 panel member on keto diets for athletes, and woo woo peddler, Ben Greenfield, would have completed his ketogenic diet fueled triathlon by now.   He has.  And for $9.99 you can get the full scoop on how it went.  No thanks.  Still, from reading the comments, one can surmise how he fared.

First, let me say this.  My hat goes off to anyone that can complete one of these races in any amount of time, etc. and all that jazz.  But at Ben's level, people don't generally compete in these things for recreation, there's money at stake -- whether it be endorsements/sponsorships or less directly involved in promoting his business.   So this was yet another publicity stunt, which is fine, but it doesn't seem to have been a success from any other viewpoint.  

I'm not a fan of his delivery, but Durian Rider is in fine form there in comments laughing at Ben.  

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The LoBAG Diets for treatment of Type II Diabetes and IGF-I: Updated & Expanded

Bump ...

Does dietary protein raise blood glucose?  Not in normal or Type 2 diabetics it doesn't.  This will be the topic of a post today or tomorrow.  There is a disturbing, in my opinion, trend in the low carb community to now demonize protein.  Your usual Atkins style diet is no longer "good enough" or "well formulated" enough for most.  This keto kraze has gotten really krazy!

As far as I'm concerned, the danger of people like Jimmy Moore is no better epitomized than by this trend.  You have lots of people regurgitating his claims that his liver makes too much glucose out of protein and this is implicated in his weight issues.  Nevermind all of the evidence to the contrary.  Leaving weight loss aside, yes, this is anecdotal, but we have no other "evidence" to go by!  Long term low carbers seem to have worsening glucose tolerance over time.  Almost to a one, and these are people who were not diabetic or in some cases even IR (by HOMA) at baseline.  

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The Cause of Hyperglycemia in Type 2 Diabetes

I will forever be grateful to (former?) blogger LynMarie Daye of Adipo Insights blog for bringing the following paper to my attention:

Insulin: understanding its action in health and disease

If you're a regular reader and you haven't read it yet, what are you waiting for?  If you're a new reader it's a must (unless of course you're just here for the gossip you claim is boring and inappropriate - grin).   The article is quite long, but it is written in very understandable fashion.  A lot of info, so perhaps best digested in small segments, but well worth the effort. 

The article begins with a history lesson about a physiology professor named Sir Edward Schafer, who "appears to have named insulin and described its actions" in a book published in 1916 entitled The Endocrine Organs.  Schafer, described a substance with dual and simultaneous functions: 

• Autacoid:  excitatory or stimulatory, e.g. glucose transport, lipid synthesis 
• Chalone:  inhibitory, e.g. inhibiting lipolysis, gluconeogenesis, ketogenesis

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Paleo Water?!

A quickie here, but I know many of my readers don't do the whole social media thing and this is just too something for words (can't even think of a good adjective there!)  

I try and read Jimmy's stuff in a reader to avoid the ads, but there it was ... screenshot right.

So I couldn't resist clicking ... and no, it's not April Fool's Day and no it's not a spoof!  Awww shucks ... you go to the link today and the paleo header is not displaying at the moment :(  It was a Geico-style cave man juxtaposed with Jimmy Moore's "The Thinker" and the LLVLC promo.  Hope they bring it back!!

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Low HbA1c is as bad or worse than high HbA1c in non-diabetics

Low Hemoglobin A1c and Risk of All-Cause Mortality Among US Adults Without Diabetes

This study looked at roughly 14,000 NHANES III participants that were not diabetic.  I think this is an important distinction because it looks at differences in normal range, "free", if you will, of what the frank hyperglycemia associated with metabolic dysfunction might do to mean and/or median values.  Here is the hazard ratio plot:  

Adjusted hazard ratios for the association between HbA1c and all-cause mortality among participants without diabetes using a quadratic spline with knots at the 2.5, 10, 50, 90, and 97.5 percentiles. Adjusted for age, race-ethnicity, sex, lifestyle factors (education, income, current smoking, alcohol consumption, physical activity, body mass index, and aspirin use), cardiovascular factors (systolic blood pressure, antihypertensive medication use, total cholesterol, HDL cholesterol, log triglycerides, elevated C-reactive protein, and history of CVD), metabolic factors (prior diagnosis of thyroid disease, thyroid-stimulating hormone, estimated glomerular filtration rate, and albuminuria), red blood cell indices (hemoglobin, red blood cell distribution width, mean cell volume, and serum folate), iron storage indices (serum albumin, ferritin, and transferrin saturation), and liver function indices (hepatitis C seropositivity, AST, and ALT). Knots were placed at 4.3%, 4.7%, 5.3%, 5.9%, and 6.2%, representing HbA1c levels at the 2.5, 10, 50, 90, and 97.5 percentiles; shaded area represents 95% CI.

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A tale of two "Wheat Bellies"

Before Dr. William Davis' name became synonymous with the elusive* Wheat Belly, he was well known for his subscription Track Your Plaque website.   This website currently charges $90 (all prices rounded) for the first year with yearly renewals at $72, for the basic membership ... more for shorter "contracts".  That's just the membership fee, that basically affords you discounts on various TYP products such as your Basic Membership Kit for $70 (reg. $110) or a Supplement Kit for $175 (reg. $215) or the testing kit for a cool $530 (reg. $570).   In the marketplace you can purchase all manner of testing supplies, etc.  

Now Davis is a huge backer of Jimmy Moore's Cholesterol Clarity book.  He contributed to it as an expert, provided an Editorial Review for Amazon.com and, as if that weren't enough, offered up a glowing 5 Star review on same, entitled Cholesterol bashing at its finest.  In it he writes:

Widely-held beliefs, many of them propagated by "official" agencies like the FDA, USDA, American Heart Association, Academy of Dietetics and Nutrition, American Diabetes Association, etc., are crumbling under the scrutiny of informed people uninfluenced by the pharmaceutical industry, agribusiness, or the excessive profiteering ways of modern "healthcare."

Uninfluenced by them, but influenced by profiteers and profiteers in their own right nonetheless.

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Where do triglycerides come from? Part I (Updated)

This post contains sufficient updates from the original (dated 5/11/11) that I consider it more of a fully updated version vs. a bump.   This began with my intent to link to this post in an upcoming discussion of triglycerides, when I noticed that Dr. Ronald Krauss was amongst the authors.   This study originally caught my eye because of   Marc Hellerstein's name, he of DNL not a major pathway in humans fame, that I've blogged on previously.

Now I have excerpted copiously from the discussion because the authors make several points relevant to the discussion of what comprises a healthy lipid profile.  As part of updating, I am breaking those excerpts up a bit more and adding some/more emphasis and additional commentary.

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